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U.S. ATSDR Publishes Draft Toxicological Profiles

by Jennifer Haggerty

As announced in the Federal Register on June 13, 2017, the Agency for Toxic Substances and Disease Registry (ATSDR) has published four draft toxicological profiles that are open for public comment. Draft profiles are available for Antimony, 2,4-D, Molybdenum, and Silica.

Under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), requirements were established for ATSDR to prepare toxicological profiles for hazardous substances on the CERCLA National Priorities List (NPL), also referred to as the Substances Priority List (SPL). The peer-reviewed profiles characterize the toxicological and adverse health effects of substances on the SPL. ATSDR uses available, key literature sources to create each profile, which represents the agency’s best efforts to provide important health information on priority substances.

ATSDR is seeking additional, relevant study information for these four draft profiles. The public comment period for these drafts is open until September 11, 2017. Information can be submitted electronically or through the mail. Once information has been received, ATSDR will evaluate the quality and relevance of submitted studies to determine if they should be included in the toxicological profile.

{ Recommended Action Items }

  • Determine if you have additional toxicological information that you want to submit for any of the four substances.
  • Submit any relevant study information by September 11, 2017.


Department of Health and Human Services, Agency for Toxic Substances and Disease Registry, “Availability of Draft Toxicological Profiles: Antimony; 2,4-D; Molybdenum; Silica.” Federal Register 82 (13 June 2017): 27066-27067:

Department of Health and Human Services, Agency for Toxic Substances and Disease Registry toxicological profiles: